Comments on Spinal Muscular Atrophy Research News: Mogul Using $100 Million in Race to Cure Daughter ...

Is this company working on ALS & SMA ? CALGA...

2011-09-27T15:58:47.290-05:00

Is this company working on ALS & SMA ?

CALGARY, ALBERTA--(Marketwire - Sept. 27, 2011)

The Company also wishes to announce a presentation at the World Stem Cell Conference, Pasadena, CA, on Wednesday, October 5, 2011 at 1 PM entitled "Prolactin Stimulates Endogenous Stem Cell Mediated Remyelination in Animal Models of Central Nervous System Injury". The presentation shall be made by Dr Allen Davidoff, Chief Scientific Officer of the Corporation'.

http://tinyurl.com/3sewqez

http://stemcellthera.com/Home.aspx

Bioengineers reprogram muscles to combat degenerat...

2011-09-22T14:01:05.441-05:00

Bioengineers reprogram muscles to combat degeneration

IMAGE: Mature muscle fibers were marked to glow green.
Click here for more information.

Berkeley — Researchers at the University of California, Berkeley, have turned back the clock on mature muscle tissue, coaxing it back to an earlier stem cell stage to form new muscle. Moreover, they showed in mice that the newly reprogrammed muscle stem cells could be used to help repair damaged tissue.

The achievement, described in the Sept. 23 issue of the journal Chemistry & Biology, "opens the door to the development of new treatments to combat the degeneration of muscle associated with muscular dystrophy or aging," said study principal investigator Irina Conboy, UC Berkeley assistant professor of bioengineering.

Skeletal muscle tissue is composed of elongated bundles of myofibers, which are individual muscle cells (myoblasts) that have fused together. This fusion of individual cells is considered the final step of skeletal muscle differentiation.

http://www.eurekalert.org/pub_releases/2011-09/uoc--brm091611.php

Stem cells are put to the test The hope is to he...

2011-09-21T07:12:50.134-05:00

Stem cells are put to the test

The hope is to help not just the 11,000 people who suffer spinal cord injuries every year, but the many more living with neural damage due to stroke, cerebral palsy, Parkinson's or Lou Gehrig's disease.

http://www.mercurynews.com/health/ci_18941860?nclick_check=1

Gene Therapy Shows Promising Results for SMA 17th...

2011-09-18T16:55:37.315-05:00

Gene Therapy Shows Promising Results for SMA 17th Sep 2011

http://www.jtsma.org.uk/iqs/dbitemid.1074/sfa.view/latest_research_news.html

Molecular Muscle Pathology in SMA 17th Sep 2011

http://www.jtsma.org.uk/iqs/dbitemid.1073/sfa.view/latest_research_news.html

New Class of Stem Cell-Like Cells Discovered in Sp...

2011-09-15T12:18:41.781-05:00

New Class of Stem Cell-Like Cells Discovered in Spinal Cord Offers Possibilities for Spinal Cord Repair

The research team utilized the Allen Spinal Cord Atlas, a finely detailed genome-wide map of gene expression throughout the mouse spinal cord, to compare the genes expressed, or turned on, in adult spinal cord radial glia with those found in other neural stem cells, revealing a signature set of 122 genes that indicate the likeness of these cells to classic neural stem cells.

The nervous system has historically been thought to be incapable of repairing itself, as the cells used to create it are exhausted during development. With the identification of these new stem cell-like radial glial cells, it may be possible to activate a certain set of genes in order to encourage those cells to reconstruct a damaged network in the adult spinal cord.

"By using the Allen Spinal Cord Atlas, we were able to discover a brand new cell type that has previously been overlooked and that could be an important player in all manner of spinal cord injury and disease, including multiple sclerosis and ALS," said Jane Roskams, Ph.D., neuroscientist at the University of British Columbia and senior author of the study.

From disabled veterans to those afflicted with Lou Gehrig's disease (ALS) or Spinal Muscular Atrophy, spinal cord related diseases and disorders affect people of all ages including nearly one-quarter of a million Americans who have suffered from a spinal cord injury; as many as 30,000 Americans who suffer from ALS at any given time; and approximately 2.5 million people worldwide who suffer from multiple sclerosis.
http://www.prnewswire.com/news-releases/new-class-of-stem-cell-like-cells-discovered-in-spinal-cord-offers-possibilities-for-spinal-cord-repair-129882783.html

IPierian returning to stem cell roots under new CE...

2011-09-12T17:06:12.216-05:00

IPierian returning to stem cell roots under new CEO

IPierian will apply IPS cells to discover new drugs in neurodegenerative diseases like Alzheimer’s and — stop me if you’ve heard this before — ALS and spinal muscular atrophy.

http://www.bizjournals.com/sanfrancisco/blog/biotech/2011/09/ipierian-returning-to-stem-cell-roots.html?page=all